Smoldering Myeloma Associated with Zonisamide Treatment.
نویسندگان
چکیده
منابع مشابه
Smoldering myeloma associated with zonisamide treatment.
A 39-year-old man was found to have hyperproteinemia after being treated with zonisamide for 10 years. Laboratory examination revealed a serum M-protein which consisted of IgG (lambda) and an increased number of plasma cells in the bone marrow, resulting in a diagnosis of smoldering myeloma. Considering his age, zonisamide was suspected to play an etiologic role in the occurrence of smoldering ...
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Multiple myeloma (MM) is a hematologic malignancy of the plasma cell that causes symptoms of bone pain, renal failure, and anemia. It is usually preceded by a precursor disease state, such as smoldering multiple myeloma (SMM) or monoclonal gammopathy of undetermined significance (MGUS), and traditional dogma dictates that treatment should be initiated on frank MM symptom development. Emerging e...
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Smoldering multiple myeloma (SMM) is an asymptomatic precursor stage of multiple myeloma (MM) characterized by clonal bone marrow plasma cells (BMPC) ≥ 10% and/or M protein level ≥ 30 g/L in the absence of end organ damage. It represents an intermediate stage between monoclonal gammopathy of undetermined significance (MGUS) and symptomatic MM. The risk of progression to symptomatic MM is not un...
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Smoldering multiple myeloma (SMM) is an asymptomatic plasma cell disorder defined in 1980 by Kyle and Greipp on the basis of a series of six patients who met the criteria for multiple myeloma (MM) but whose disease did not have an aggressive course [1]. At the end of 2014, the International Myeloma Working Group (IMWG) updated the definition, and SMM is now defined as a plasma cell disorder cha...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 2002
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.41.138